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Janumet XR

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Janumet XR is a prescription medication used to improve blood sugar control in adults with type 2 diabetes. This medication combines two active ingredients, sitagliptin and metformin extended-release, to help control blood sugar levels. Sitagliptin works by increasing the levels of natural substances called incretins which help control blood sugar by increasing insulin release, especially after a meal. Metformin works by decreasing glucose (sugar) production in the liver and decreasing absorption of glucose by the intestines.

How is this medication used?

Janumet XR should be taken once daily with a meal to reduce the risk of an upset stomach. Swallow the tablets whole; do not crush, chew, or cut them. The dosage of Janumet XR must be determined by your doctor and may vary depending on your medical condition, kidney function, and response to treatment.

What are the possible side effects?

Common side effects of Janumet XR include nausea, vomiting, stomach upset, diarrhea, and a metallic taste in the mouth. More serious side effects can include lactic acidosis, a condition characterized by muscle pain, trouble breathing, stomach pain, dizziness, and feeling cold, especially in the arms and legs. An allergic reaction to this drug is rare but seek immediate medical attention if it occurs.

What are the potential interactions?

Janumet XR can interact with a number of medications and conditions. It should not be used with alcohol or when undergoing radiologic studies involving iodinated contrast, as both can increase the risk of lactic acidosis. Inform your doctor of all medications you are taking, including prescription and over-the-counter drugs, vitamins, and herbal products, to avoid potential interactions.

Disclaimer: The information provided on this website is for informational purposes only and is not intended as medical advice. Always consult with your healthcare provider for medical advice, diagnosis, or treatment. Images are for representation purposes only and actual packing may differ by brand and/or manufacturer.