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Rexulti

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Rexulti (brexpiprazole) is an atypical antipsychotic medication used for the treatment of schizophrenia and as an add-on therapy for adults with major depressive disorder (MDD) who have not responded adequately to antidepressants alone. It works by helping to restore the balance of certain natural substances in the brain (neurotransmitters).

How is this medication used?

Rexulti is taken by mouth, with or without food, usually once daily as prescribed by a healthcare professional. The dosage is based on your medical condition, response to treatment, and other medications you may be taking. It is important to follow your doctor's instructions closely and not to adjust your dose or frequency without consulting your doctor.

What are the possible side effects?

Possible side effects of Rexulti include weight gain, headache, dizziness, drowsiness, restlessness, and gastrointestinal issues such as nausea and constipation. More serious side effects can include increased risk of stroke in elderly patients with dementia-related psychosis, suicidal thoughts and behavior in adolescents and young adults, and other severe neurological and metabolic side effects.

What are the potential interactions?

Rexulti may interact with other medications and substances, which can increase side effects or reduce the effectiveness of Rexulti or the other drugs. These include certain antidepressants, antifungal medications, antihistamines, opioid pain or cough relievers, sleeping or anxiety medications, muscle relaxants, and drugs that may affect the heart rhythm (QT prolongation). Always inform your healthcare provider about all the drugs and supplements you are taking before starting Rexulti.

Disclaimer: The information provided on this website is for informational purposes only and is not intended as medical advice. Always consult with your healthcare provider for medical advice, diagnosis, or treatment. Images are for representation purposes only and actual packing may differ by brand and/or manufacturer.