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Xolair

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Xolair, generically known as omalizumab, is a prescription medication used to manage and treat moderate to severe persistent asthma in patients whose symptoms are not adequately controlled with inhaled corticosteroids. It is also indicated for chronic idiopathic urticaria (CIU) in patients who continue to exhibit symptoms despite H1 antihistamine treatment. Xolair is a monoclonal antibody that inhibits the interaction between IgE and the high-affinity IgE receptor on the surface of mast cells and basophils, thus reducing the release of allergy-related mediators.

How is this medication used?

Xolair is administered by subcutaneous injection. The dosage and frequency of administration depend on the patient's weight and serum IgE levels, which must be measured before the start of treatment. For asthma treatment, Xolair injections are typically given once every two or four weeks. For chronic idiopathic urticaria, dosing frequency is determined by the treating physician based on the patient's response. It is crucial to follow the healthcare provider's instructions precisely and not to adjust the dose or frequency without consultation.

What are the possible side effects?

Common side effects of Xolair include joint pain, dizziness, tiredness, skin rash, hair loss, and injection site reactions such as pain, bruising, and swelling. More serious side effects may include severe allergic reactions, an increased risk of heart attack and stroke, blood vessel inflammation, and an elevated risk of certain parasitic infections. Patients should seek immediate medical attention if they experience symptoms of an allergic reaction, such as trouble breathing, swelling of the face, lips, tongue, or throat, or if they have any severe or concerning symptoms.

What are the potential interactions?

Before using Xolair, patients should inform their healthcare provider about all the other medications they are taking, as Xolair can interact with other drugs. Specifically, it may interact with medications that suppress the immune system, increasing the risk of infections, or with certain allergen immunotherapy treatments. The healthcare provider will assess any potential interactions on a case-by-case basis to ensure safe use of Xolair in conjunction with other medications.

Disclaimer: The information provided on this website is for informational purposes only and is not intended as medical advice. Always consult with your healthcare provider for medical advice, diagnosis, or treatment. Images are for representation purposes only and actual packing may differ by brand and/or manufacturer.